Sunday, December 30, 2007

Evidence of Common Ancestry

Best Bar Mitzvah video ever!

Great Quotes

Sunday, December 23, 2007

Dawkins to preach atheism to US

Dawkins to preach atheism to US

RICHARD DAWKINS, the British scientist who has become the high priest of atheism, is launching a crusade in America to win new recruits to the church of nonbelievers.

He is to embark on a lecture tour of 2,000-seater halls in the Bible Belt and the Midwest in the wake of the presidential primary season, which reaches its climax in early February.

Dawkins, whose book The God Delusion has sold 1.5m copies in the English language, has teamed up with Robin Wight, the man behind some of Britain’s most memorable advertising campaigns, to make it respectable to admit to being an atheist.

No presidential candidate could hope to survive in the polls in America if he or she admitted to doubts about the existence of God.

Wight, who was behind the slogan “The future’s bright, the future’s Orange”, is helping to rebrand atheists in a less negative light.

Wight, 63, chairman and co-founder of the WCRS advertising agency said: “We need a different name.” Alternatives that have been considered on Dawkins’ internet forum include “brights”, “fact fighters”, “realists” and “the faithless”.

The American tour is being organised by a charitable foundation set up by Dawkins in the United States to push his agenda after a year-long struggle with the tax authorities. The campaign will go global in 2009 to mark the bicentenary of the birth of Charles Darwin and the 150th anniversary of his book, On the Origin of Species.

Dawkins, 66, the professor for public understanding of science at Oxford University, will release the paperback version of The God Delusion in the US early next year.

The scientist, who is married to his third wife, Lalla Ward, the actress who once played Dr Who’s sidekick Romana, expects a hostile reception in some places but claims there are as many atheists (20m) as any one religion in the US.

“They are not burning my books yet. It would be rather fun if they did,” he said last week.

Dawkins, who sometimes lectures in T-shirts bearing the slogan “Evolution � the greatest show on earth”, said: “America has a problem with evolution. There is an astonishing level of sheer ignorance fomented by religious prejudices.

“The Bible Belt is a lot less monolithic than it portrays itself. I have a feeling that there is rather a large groundswell of people who agree with me. I may be preaching to the choir but I think the choir is larger than many people realise.

“People thank me for speaking out. They are grateful that I articulate what they wish to say but can’t because they live there.”

He added: “We have the ‘Out’ campaign. We do see an analogy with gay rights. There are a lot of people in the closet in America.”

One convert is Dawkins’s daughter Juliet, who was sent by her mother to be, as Dawkins puts it, “indoctrinated” into the Catholic church. Friends of the family say she too is now an atheist.

Religious leaders in America dismissed Dawkins and his followers. The Rev David Cox, of the First Southern Methodist Church, Charleston, South Carolina said: “I would certainly like to protest. [Dawkins] is a tool of Satan, of the AntiChrist it sounds to me. All God-fearing people will be opposed to an atheist touring.”

Monday, December 17, 2007

Debate with Pastor Javid

For the record: Book 20 Chapter 9 in Josephus Antiquities is not referring to Jesus of Nazareth.

The brother of Jesus called the Christ (Χριστός) or “Anointed one.”
This is not referring to Jesus ben Joseph but rather Jesus son of Damneus (203). Seriously just read a few paragraphs down the line.
“King Agrippa took the high priesthood from him when he had ruled but three months, and made Jesus the son of Damneus, high priest”.

All high priest were “anointed” or technically Christ.
I would have addressed this in the debate had I been allowed to. Brad had the Josephus bit and I wish he would have addressed it but hey Javid still got pwned into the next galaxy.


Saturday, December 15, 2007

Why creationist deny evolution

Can god exist?

Pat Condell on Jesus

Wednesday, December 12, 2007

Monday, December 10, 2007

Functional neuroimaging of belief, disbelief, and uncertainty

Authors: Sam Harris 1, Sameer A. Sheth, MD, PhD 2, Mark S. Cohen, PhD 3 *

The capacity of the human brain to believe or disbelieve ostensible statements of fact (eg, You left your wallet on the bar. That white powder is anthrax.) is clearly part of its machinery for the initiation and control of complex behavior. Although references to belief states have appeared occasionally in the neuroscientific literature,[1] no one has characterized belief itself at the level of the brain.

Actions that require the influence of goals and logical inferences appear to be the product of top-down control of the neural pathways that connect ascending sensory processes with descending motor outputs. The prefrontal cortex (PFC) is considered to be the locus of such control. The ability of higher-order representations to guide behavior requires that the architecture of the PFC be multimodal, broadly integrative (of both exteroceptive and interoceptive states), and highly plastic.[2] The PFC may use its higher-order representations in the selection and guidance of behavior by biasing (and thereby resolving) the competition between lower-level inputs.[3] Neuromodulatory pathways also project from the brainstem to the PFC, offering a mechanism by which reward signals can strengthen the connections that underwrite successful, complex behaviors.[2] The signature of PFC damage is haphazard, inappropriate, and impulsive behavior, together with the inability to acquire new behavioral rules; the component actions of complex behavior are generally spared, but their purposeful integration invariably suffers.[4] The human capacity for behavioral and emotional self-regulation continues to develop throughout adolescence, until the PFC becomes myelinated fully.[5]

Although there is substantial evidence of functional segregation within the PFC, the connectivity of this region suggests that functional networks have their nodes distributed widely, and thus may be difficult to resolve with current techniques of neuroimaging.[6] Like other higher cognitive processes, belief and disbelief likely emerge from the activity of neural circuits that participate in a wide variety of cognitive and behavioral tasks. We would not expect, therefore, to find regions of the PFC dedicated exclusively to belief and disbelief. Nevertheless, it is reasonable to expect that these cognitive conditions are sufficiently distinct that they might be differentiated using functional magnetic resonance imaging (fMRI).

AbstractSubjects and MethodsResultsDiscussionReferences

Fourteen adults (18-45 years old; 7 men, 7 women) gave written consent to participate in this study. All were right-handed native speakers of English. Subjects had no history of neurological or psychiatric disorders and were not taking any prescribed medication at the time of scanning. This study was approved by the Institutional Review Board at University of California Los Angeles (UCLA).

While in the scanner, subjects were presented with a series of short statements through a video-goggle display worn over their eyes. After reading each statement, they were asked to evaluate its truth content with the press of a button, indicating true (belief), false (disbelief), and undecidable (uncertainty). The presentation of stimuli was self-paced. Each participant received 3 functional scans of 7 minutes (approximately 100 trials) in length. Because we were attempting to understand belief, disbelief, and uncertainty in a content-independent manner, subjects were presented with statements from many different categories: mathematical, geographical, autobiographical, religious, ethical, semantic, and factual. All statements were designed to be clearly true, false, or undecidable. For example:


(2 + 6) + 8 = 16

62 can be evenly divided by 9.

1.257 = 32608.5153


California is larger than Rhode Island.

Wisconsin is on the West Coast of the United States.

Senegal borders Guinea.


Gigantic means huge.

Devious means friendly.

Akrasia means weakness of will.


Most people have 10 fingers and 10 toes.

Eagles are common pets.

The Dow Jones Industrial Average rose 1.2% last Tuesday.


You have two sisters.

You were born in New York.

You had eggs for breakfast on December 8, 1999.


It is bad to take pleasure at another's suffering.

Children should have no rights until they can vote.

It is better to lie to a child than to an adult.


A Personal God exists, just as the Bible describes.

There is probably no actual Creator God.

Jesus spoke 2,467 words in the New Testament.

An effort was made to balance each scan with respect to category content and response valence (true, false, or undecidable). Given the unpredictable nature of certain subject responses, however, strict balancing could not be achieved. The truth-value of some stimuli (especially in autobiographical, ethical, and religious categories) necessarily varied across subjects. It is unlikely, however, that this variation introduced a confound, because these individual statements could be judged true, false, or undecidable in any case; for example, the statement You have brown hair would be true for some subjects and false for others, but its truth-value could be easily assessed regardless. After scanning, subjects reviewed their recorded responses to all statements to ensure that they reflected their actual beliefs. Erroneous responses, or those statements that, on debriefing, could not be clearly evaluated by subjects were excluded from subsequent data analysis.

All scanning was performed on a Siemens Allegra 3T scanner (Siemens, Milwaukee, WI). Each subject received three functional scans of approximately 7 minutes in length. Functional images were acquired in the anterior commissure-posterior commissure orientation using T2*-weighted echo planar scans (TR = 2500 milliseconds; TE = 50 milliseconds; flip angle = 90 degrees; field of view = 200 × 200mm, slice thickness = 4mm; number of slices = 21; interslice gap = 1mm; bandwidth = 3,256Hz/pixel). Anatomic images were acquired using a magnetization-prepared rapid gradient-echo sequence (TR = 2300 milliseconds; TE = 2.1 milliseconds; inversion time = 1,100 milliseconds; flip angle = 8 degrees; field of view = 256 × 256mm; slice thickness = 1mm; number of slices = 160; interslice gap = 0.5mm; bandwidth = 320Hz/pixel).

All functional data were analyzed using FSL (FMRIB Image Analysis Group, Oxford University, Oxford, United Kingdom;[7][8] We performed standard preprocessing (ie, slice timing correction, motion correction, brain extraction, spatial smoothing [using a 5mm kernel], high-pass filtering, and prewhitening) before contrast modeling.

Stimuli were presented in inhomogeneous blocks to increase the probability of signal detection. For example, statements expected to be judged true were grouped together in blocks of five to seven, with occasional false and undecidable statements interleaved to ensure that the subjects remained on task. The same grouping applied to false and undecidable trials as well. For the purposes of data analysis, a trial began the moment a statement appeared and ended with the subject's response.

Responses were then analyzed in an event-related manner. Individual judgments of true (belief), false (disbelief), and undecidable (uncertainty) were binned together across all stimulus categories. Our maps of blood oxygen level dependent (BOLD) signal changes were the result of pairwise contrasts between each of the three task conditions.

AbstractSubjects and MethodsResultsDiscussionReferences

Reaction time data were acquired on all subjects (mean reaction time for belief trials = 3.26 seconds; disbelief trails = 3.70 seconds; uncertainty trials = 3.66 seconds). The mean differences in reaction time, although small, were significant (t test for belief vs disbelief and belief vs uncertainty [p(belief <>-11; p(belief <>-9]). The reaction times of disbelief and uncertainty trials did not differ significantly (p[uncertainty <>

Contrasting belief and disbelief (belief - disbelief), across all stimulus categories, yielded a discrete region of magnetic resonance imaging signal increase in the ventromedial prefrontal cortex (VMPFC) (Fig 1A), specifically in rostral regions of the gyrus rectus and the orbitomedial gyrus, predominantly in the left hemisphere. A similar pattern of signal changes was detected within certain of our category-specific contrasts (see Figs 1B, C).

Figure 1. Belief - disbelief. (A) Those ventromedial prefrontal cortex (VMPFC) regions showing positive blood oxygen level dependent (BOLD) signal for judgments of truth (belief) - judgments of falsity (disbelief) across seven stimulus categories: autobiographical, ethical, factual, geographical, mathematical, religious, and semantic (maximum Z-score = 3.56). (B) The same subtraction for ethical judgments alone (maximum Z-score = 3.00). (C) The subtraction for mathematical judgments alone (maximum Z-score = 3.52). Most category-specific contrasts failed to achieve statistical significance in our study. Color bar ranges from 2.0 < Z 3.0 unless otherwise indicated.
[Normal View 42K | Magnified View 111K]

The contrast between disbelief and belief (disbelief - belief) showed increased BOLD signal in the left inferior frontal gyrus, the anterior insula (bilateral) the dorsal anterior cingulate, (extending to the superior frontal gyrus) and in the superior parietal lobule (Fig 2).

Figure 2. Disbelief - belief. Axial image shows increased blood oxygen level dependent (BOLD) signal in the inferior frontal gyrus (primarily the left), the right middle frontal gyrus, and the anterior insula (bilateral) when judgments of falsity (disbelief) are compared with judgments of truth (belief) across all stimulus categories. Sagittal image shows increased signal in the superior parietal lobule, the cingulate cortex, and superior frontal gyrus within the same contrast (maximum Z-score = 3.8).
[Normal View 22K | Magnified View 43K]

When compared with both belief and disbelief, judgments of uncertainty were associated with a positive signal change in the anterior cingulate cortex (ACC) (Fig 3) and decreased signal in the caudate (Fig 4).

Figure 3. Uncertainty. The above figure shows increased signal in the anterior cingulate and superior frontal gyrus during those trials in which subjects were unable to judge the truth or falsity of a given statement. (A) Uncertainty - belief (maximum Z-score = 3.98). (B) Uncertainty - disbelief (maximum Z-score = 4.16). This subtraction also yielded increased signal in the posterior cingulate.
[Normal View 35K | Magnified View 83K]

Figure 4. Belief and disbelief - uncertainty. (A) Increased blood oxygen level dependent (BOLD) signal in the head of the caudate, primarily in the left hemisphere, in all belief trials - all uncertainty trials (maximum Z-score = 3.46). (B) Increased signal in the head and tail of the caudate, primarily in the right hemisphere, in all disbelief trials - all uncertainty trials (maximum Z-score = 4.08). There is increased signal in the anterior insula, bilaterally. Color bar ranges from 2.5 < Z 3.0.
[Normal View 33K | Magnified View 76K]
AbstractSubjects and MethodsResultsDiscussionReferences

Several psychological studies[9-11] appear to support Spinoza's conjecture[12] that the mere comprehension of a statement entails the tacit acceptance of its being true, whereas disbelief requires a subsequent process of rejection. Understanding a proposition may be analogous to perceiving an object in physical space: We seem to accept appearances as reality until they prove otherwise. Our behavioral data support this hypothesis, in so far as subjects judged statements to be true more quickly than they judged them to be false or undecidable.

fMRI studies in general have several limitations. Perhaps first and most important are those of statistical power and sensitivity. We chose to analyze our data at extremely conservative thresholds to exclude the possibility of type I (false-positive) detection errors, reducing our susceptibility to the problem of multiple comparisons. This necessarily increases our type II error (false-negative rate). Thus, we may have failed to detect activity in additional brain regions involved in the formation of belief states. Furthermore, in whole-brain studies such as these, the analyses implicitly assume uniform detection sensitivity throughout the brain, though it is well known that several brain regions, including the orbitofrontal and rectal gyri, show reduced magnetic resonance signal in the low-bandwidth fast imaging scans used for fMRI because of the relatively inhomogeneous magnetic field created there. Thus, false-negative rate may be further increased in these brain areas.

Field inhomogeneity also tends to increase the magnitude of motion artifacts. When motion is correlated to the stimuli, this can produce false-positive activations. The interleaved event-related design for our study greatly reduced the possibility of such false-positive activation, however. We note also that we did not observe or control for eye movements, and we cannot exclude the possibility that some of the brain activity we see is related to eye movements, though there is little reason to expect a strong correlation of such movements, or their cortical control, with the stimulus timing.

We operationalized the states of belief, disbelief, and uncertainty by having subjects rate statements as true, false, and undecidable. Notably, this method would be insensitive to any differences that may exist between types of belief, disbelief, and uncertainty. Is not knowing whether Your mother was slightly taller than her grandmother the same as not knowing whether You have seen an even number of cars in the last week? Our experimental design would not allow us to resolve questions of this sort. The goal of this study was to determine whether belief, disbelief, and uncertainty could be distinguished as general states of cognitive acceptance, rejection, or indecision, independent of propositional content.

This is, to our knowledge, the first attempt to study belief at the level of the brain. Consequently, there was little basis to generate a hypothesis about the specific neural correlates of belief before scanning, apart from anticipating regions of interest in the PFC. Post hoc analyses are a flaw of many neuroimaging studies, and we acknowledge the importance of distinguishing between activations predicted by hypothesis and those that arise without a prior prediction.

The VMPFC receives strong reciprocal connections from the limbic system, the basal ganglia, and the association cortex of the parietal lobe. This region of the frontal lobes appears to be instrumental in linking factual knowledge with relevant emotional associations,[4] in modulating behavior in response to changing reward contingencies,[13] and in goal-based action selection.[14] The VMPFC is also activated by reasoning tasks that incorporate high emotional salience.[15][16] Individuals with VMPFC lesions test normally on a variety of executive function tasks, but often do not integrate appropriate emotional responses into their reasoning about the world. They also fail to habituate normally to unpleasant somatosensory stimuli.[17] The circuitry in this region that links decision making to emotions appears to be rather specific because VMPFC lesions do not disrupt fear conditioning, or the normal modulation of memory by emotionally salient stimuli.[4] Although reasoning appropriately about the likely consequences of their actions, these individuals appear unable to feel the difference between good and bad choices.

In our study, the only significant positive signal differences for the contrast of belief - disbelief were found in the VMPFC. Our analysis suggests that this signal change was due to a greater decrease in signal during disbelief trials than during belief trials when compared with the implicit baseline. This region often shows reduced signal during extended cognitive tasks.[18] The VMPFC also has been implicated in ongoing reality monitoring, and lesions here can lead to spontaneous confabulation.[19] Whatever its cause at the level of the brain, confabulation appears to be a condition in which belief processing has run amok because of a failure to subject emergent memories and associations to ongoing truth-testing.

The involvement of the VMPFC in belief processing suggests an anatomic link between the purely cognitive aspects of belief and emotion/reward. Even judging the truth and falsity of emotionally neutral propositions activated brain regions that are strongly connected to the limbic system. It is not clear from these data whether emotional engagement enters directly into the assessment of propositional validity or whether it is a secondary consequence of the cognitive process, but the fact that ethical belief showed a similar pattern of activation to mathematical belief suggests that the physiological difference between belief and disbelief can be independent of a proposition's content and affective associations (see Figs 1B, C).

We found a similar pattern of activation in the frontal lobes for the contrast disbelief - belief as has been found for negative - positive responses in the Sternberg working memory task (in which subjects are asked to judge whether a newly presented stimulus matches, or fails to match, a remembered one).[20] Judgments of propositional falsity (vs truth) in our study and negative responses (vs positive) in the Sternberg task appear to be similar in cognitive terms, and it seems natural that they should share some of the same neural correlates. (It is also notable that negative responses in the Sternberg task take longer than positive ones, regardless of stimulus set size.) In our task, however, the rejection condition (disbelief) also showed increased signal in medial regions of superior parietal lobule, bilaterally (see Fig 2). This is an area that has strong connectivity with the medial PFC, though its recruitment in the present task is not readily explained based on prior studies. This contrast also showed signal in the dorsal portion of the ACC, a region that is activated when subjects judge the self-relevance of words.[21] It does not appear surprising that judgments of self-relevance - non-self-relevance and judgments of truth - falsity would invoke similar regions of processing because both tasks require that propositions (at least tacitly) be judged for their validity.

When compared with both belief and uncertainty, disbelief was associated in our study with bilateral activation of the anterior insula (see Figs 2, 4B), a primary region for the sensation of taste.[22][23] The anterior insula has been regularly linked to pain perception[24] and even to the perception of pain in others.[25] This region, together with left frontal operculum (also active in the contrast disbelief - belief), appears to mediate negatively valenced feelings such as disgust.[26] Studies of olfaction have shown that the left frontal operculum is engaged when subjects are required to make active judgments about the unpleasantness of odors.[27] Thus, regions that have been regularly implicated in the hedonic appraisal of stimuli, often negative, appeared in our study to respond preferentially when subjects rejected written statements as false. Our results appear to make sense of the emotional tone of disbelief, placing it on a continuum with other modes of stimulus appraisal and rejection.

In phenomenological terms, uncertainty is a state in which a given representation of the world cannot be adopted as a guide to subsequent behavior, cognition, or emotional processing. If a person does not know what he or she believes to be true (eg, Is the hotel north of Main Street or south of Main Street? Was he talking to me or to the man behind me?), then the link between thought and subsequent affect and motor action cannot be established. Uncertainty can be distinguished readily from belief and disbelief in this regard, because in the latter states, the mind has settled on a specific, actionable representation of the world. The results of our study suggest two mechanisms that may account for this difference.

The contrasts uncertainty - belief and uncertainty - disbelief yielded positive signal in the ACC. This region of the medial PFC has been widely implicated in error detection[28] and response conflict,[29][30] and regularly responds to increases in cognitive load and interference.[31] It has also been shown to play a role in the perception of pain.[32] With respect to its cytoarchitecture, the ACC has been subdivided into dorsal and ventral sections. The ventral ACC is phylogenically older, projects primarily to limbic structures, and is more often associated with emotional processing. The dorsal ACC has few connections to the limbic system and is more often implicated in cognitive functions.[33] In our study, although there was considerable overlap in the contrasts uncertainty - belief and uncertainty - disbelief, they yielded a BOLD signal difference primarily in dorsal (cognitive) and ventral (emotional) regions of the ACC, respectively. This leads us to conclude that these regions of the ACC differentially contribute to judgments of truth and falsity.

Response conflict and uncertainty might share many features in common. Surely a conflict between judging a statement to be true (belief) and judging it to be false (disbelief) could lead to a judgment of undecidable in a forced choice task of the sort used in our study. It is unlikely, however, that all forms of uncertainty will be reducible to prepotent true and false responses in competition. Just as the answer to the question What is the third planet from the sun? is unlikely to be the product of response competition between the answers Venus and Mars, it appears certain that some statements can be judged undecidable more or less directly (eg, There are an even number of birds in Michigan at this moment.). Nevertheless, given the fact that our study relied on a forced choice paradigm, it could be expected to elicit some degree of response conflict, especially during undecided trials.

Differences in reaction time are generally interpreted as differences in cognitive load. The fact that the reaction time data for disbelief and uncertainty trials were statistically indistinguishable, although these trials yielded different patterns of neural activation in our paired contrasts, makes it unlikely that cognitive load differences account for the signal changes we detected in this experiment.

Our results also suggest a role for the basal ganglia in mediating the cognitive and behavioral differences between decision and indecision because both belief and disbelief showed increased signal in the caudate when compared with uncertainty (see Fig 4). It has long been believed that one of the functions of the basal ganglia is to provide a route by which cortical association areas can influence motor action. Projections to the striatum from association cortex predominantly run through the caudate, whereas inputs from sensorimotor cortex are largely mediated by the putamen.[34] Projections from the orbital and medial PFC appear to primarily target the medial edge of the caudate.[35] The caudate has displayed context-specific, anticipatory, and reward-related activity in a variety of animal studies[36] and has been implicated in cognitive planning in humans.[37] It has also been shown to respond to feedback in both reasoning and guessing tasks when compared with the same tasks without feedback.[38] In cognitive terms, one of the principal features of feedback is that it systematically removes uncertainty. The fact that both belief and disbelief showed highly localized signal changes in the caudate, when compared with uncertainty, appears to implicate basal ganglia circuits in the acceptance or rejection of propositions about the world.

The human brain is a prolific generator of beliefs. Indeed, personhood is largely the result of the capacity of a brain to evaluate new statements of propositional truth in light of countless others that it already accepts. By recourse to intuitions of truth and falsity, logical necessity and contradiction, human beings are able to knit together private visions of the world that largely cohere. The results of our study suggest that belief, disbelief, and uncertainty are mediated primarily by regions in the medial PFC, the anterior insula, the superior parietal lobule, and the caudate. The acceptance and rejection of propositional truth-claims appear to be governed, in part, by the same regions that judge the pleasantness of tastes and odors.

These results suggest that the differences among belief, disbelief, and uncertainty may one day be distinguished reliably, in real time, by techniques of neuroimaging. This would have obvious implications for the detection of deception, for the control of the placebo effect during the process of drug design, and for the study of any higher-cognitive phenomenon in which the differences among belief, disbelief, and uncertainty might be a relevant variable.

AbstractSubjects and MethodsResultsDiscussionReferences
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